A PE protein expressed by Mycobacterium avium is an effective T-cell immunogen.
نویسندگان
چکیده
Infection of mice with Mycobacterium avium or immunization with a novel PE gene expressed by M. avium (MaPE) showed that a dominant T-cell immune response was elicited. Immunization with an MaPE DNA vaccine protected mice against an aerosol challenge with Mycobacterium tuberculosis, suggesting that mycobacteria express PE antigens with cross-protective T-cell epitopes.
منابع مشابه
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ورودعنوان ژورنال:
- Infection and immunity
دوره 74 1 شماره
صفحات -
تاریخ انتشار 2006